N-tert-Butoxycarbonyl-5-cyano-1H-indole-2-boronic acid

N-tert-Butoxycarbonyl-5-cyano-1H-indole-2-boronic acid - Names and Identifiers

Name	1-Boc-5-Cyanoindole-2-boronic acid
Synonyms	1-BOC-5-CYANO-2-INDOLEBORONIC ACID 1-Boc-5-Cyanoindole-2-boronic acid 1-BOC-5-CYANOINDOLE-2-BORONIC ACID 1-Boc-5-cyano-1H-indole-2-bornic acid N-BOC-5-CYANO-1H-INDOLE-2-BORONIC ACID 1-BOC-5-CYANO-1H-INDOLE-2-BORONIC ACID 5-CYANOINDOLE-2-BORONIC ACID, BOC PROTECTED 5-CYANO-1-TERT-BUTOXYCARBONYLINDOLE-2-BORONIC ACID N-TERT-BUTOXYCARBONYL-5-CYANO-1H-INDOLE-2-BORONIC ACID N-tert-Butoxycarbonyl-5-cyano-1H-indole-2-boronic acid [1-(tert-butoxycarbonyl)-5-cyano-1H-indol-2-yl]boronic acid
CAS	475102-15-9
InChI	InChI=1/C14H15BN2O4/c1-14(2,3)21-13(18)17-11-5-4-9(8-16)6-10(11)7-12(17)15(19)20/h4-7,19-20H,1-3H3

N-tert-Butoxycarbonyl-5-cyano-1H-indole-2-boronic acid - Physico-chemical Properties

Molecular Formula	C14H15BN2O4
Molar Mass	286.09
Density	1.21g/cm³
Melting Point	260-270
Boling Point	509.1°C at 760 mmHg
Flash Point	261.7°C
Vapor Presure	3.46E-11mmHg at 25°C
Storage Condition	Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
Refractive Index	1.566

N-tert-Butoxycarbonyl-5-cyano-1H-indole-2-boronic acid - Risk and Safety

Hazard Symbols	Xi - Irritant
Hazard Note	Irritant/Keep Cold

N-tert-Butoxycarbonyl-5-cyano-1H-indole-2-boronic acid - Introduction

Acid is an organic compound with the following properties:

1. Appearance: White to yellow solid.
2. molecular formula: C18H20BN3O4.
3. Molecular weight: 349.18g/mol.
4. Solubility: Soluble in some organic solvents, such as dimethyl sulfoxide and dichloromethane.
5. melting point: about 135-140 ℃.

Its use mainly includes the following aspects:

1. organic synthesis: can be used as an important intermediate in organic synthesis, for the synthesis of various pyrrole, carbazole and other indole compounds.
2. drug research: can be used for the synthesis of bioactive pyrrole, carbazole and other indole drug molecules for drug research and development.
3. chemical reaction: it can be used as a ligand to participate in the synthesis reaction of metal complexes, and further expand its application field.

The preparation method of the compound can generally be achieved by the following steps:

1. 5-cyanoindole is reacted with Boc2O to generate 1-Boc-5-cyanoindole.
2. React 1-Boc-5-cyanoindole with boron acid and alkali to generate acid.

The safety information for this compound is currently not clearly reported, so it is necessary to follow general laboratory safety procedures when using it. Also, avoid contact with skin, eyes and mucous membranes during handling and storage. If accidental contact occurs, rinse immediately with plenty of water and seek medical help.

Last Update：2024-04-10 22:40:09